I will go ahead and post the steps for the Xbox One, Physically power cycling on the Xbox 360 is the same, just hold down the power button until the console turns off. If the issue persists then I would advise that you Physically Power Cycle your console. Rocksmith Remastered comes with over 50 songs, Guitarcade modes to gamify your learning experience, online leaderboards, a streamlined interface, and much more. Have you tried connecting to all USB ports on the console including the front and back. It dynamically adjusts the difficulty to your skill level, then slowly introduces more notes and phrases until you’re playing your favorite songs note-for-note.
The manufacturer-provided diagram and explanation of how to add a separate speaker were mind-numbingly.
Try removing any other USB devices that draw power and see if it makes a difference. If the port you're using is part of the same 'root hub' that is being used by something else that draws power you might not be left with enough power to 'drive' the cable (the cable is an audio interface). Rocksmith 2014 Edition is compatible with the original Rocksmith Real Tone Cable that plugs any real guitar directly into an Xbox 360®, PS3, PC, or Mac.
By replicating this cable’s outputs, you can still play the instrument in the game. This design lets you connect the guitar to your gaming console. The Real Tone Cable from Rocksmith is a 1/4-inch standard guitar jack on one end and a USB connection on the other. Over 95 of players have improved their guitar skills. The cable also requires power from the USB port. How to Play Rocksmith without a Real Tone Cable.
Rocksmith is a music video game series which aims to teach guitar by letting you plug in virtually any guitar or bass and becomes your personal guitar teacher as it monitors how you play. So I just installed Rocksmith 2014 Remastered on an X Box 1. Rocksmith 2014 Edition (w/ Cable) (English) A proven method to learn guitar fast National research studies have found that Rocksmith is the fastest way to learn guitar.